Angioedema (Sunday Scary)
Now to the Scary -- ANGIOEDEMA Background -- Angioedema is a paroxysmal, non-demarcated swelling of dermal or submucosal layers of skin / mucosa. Swelling is typically asymmetric, non-pitting and nonpruritic but can be associated with allergic features. isolated uvular angioedema (Quincke's disease) is a rare presentationcauses: trauma, inhalation, general anesthesia, meds (ACEI), infections, hereditary Etiologies ACE-I (bradykinin) Hereditary Autosomal DominantC1 esterase deficiency --> unregulated bradykinin associated with compli
by